This was a contribution to the International Atomic Energy Agency's Bulletin. The Clean Energy Ministerial Flexible Nuclear Campaign co-founded by Kirsty Gogan and Eric Ingersoll explores the expanded role that nuclear energy can play in de-risking the energy transition. Here, we describe two opportunities to drive deeper decarbonization with nuclear energy: 1) expand role of nuclear energy in electricity production through a combination of advanced reactors and thermal energy storage to complement renewables in future energy grids; 2) address the use of oil and gas by providing large-scale, low-cost hydrogen produced with nuclear power.